Yao, Fenmei,Peng, Ge,Ludwikow, Maria J.,Gallop, Mark A.,Phan, Thu
申请号：
AU2010219384
公开号：
AU2010219384B2
申请日:
2010.09.10
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
#$%^&*AU2010219384B220120119.pdf#####CXNRPonblDCC RXS 17741I(.I DOC-11)/19/21>；11 ABSTRACT The disclosures herein relate generally to acyloxyalkyl carbamate prodrugs of (±) 4 amino 3 (4 chlorophenyl)butanoic acid and analogs thereof, pharmaceutical compositions thereof, 5 methods of making prodrugs of (±) 4 amino 3 (4 chlorophenyl)butanoic acid and analogs thereof, methods of using prodrugs of (±) 4 amino 3 (4 chlorophenyl)butanoic acid and analogs thereof, and pharmaceutical compositions thereof for treating or preventing common diseases and/or disorders such as spasticity and/or acid reflux disease. The disclosures herein also relate to acyloxyalkyl carbamate prodrugs of (±) 4 amino 3 (4 10 chlorophenyl)butanoic acid and analogs thereof which are suitable for oral administration and to sustained release oral dosage forms thereof.
