Bernd Jandeleit;Mark A. Gallop;Noa Zerangue;Yunxiao Li
发明人:
Noa Zerangue,Bernd Jandeleit,Yunxiao Li,Mark A. Gallop
申请号：
US12835663
公开号：
US08372881B2
申请日:
2010.07.13
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Acyloxyalkyl carbamate prodrugs of trans-4-(aminomethyl)-cyclohexanecarboxylic acid, pharmaceutical compositions thereof, methods of making prodrugs of trans-4-(aminomethyl)-cyclohexane-carboxylic acid, and methods of using prodrugs of trans-4-(aminomethyl)-cyclohexanecarboxylic acid and pharmaceutical compositions thereof to treat or prevent various diseases or disorders are disclosed. Acyloxyalkyl carbamate prodrugs of trans-4-(aminomethyl)-cyclohexanecarboxylic acid and pharmaceutical compositions thereof suitable for oral and topical administration and for administration using sustained release dosage forms are also disclosed.
