Bömer, Dr. Ulf,Bothe, Dr. Ulrich,Friedrich, Dr. Christian,Günther, Dr. Judith,Hauff, Dr. Peter,Lange, Dr. Martin,Nubbemeyer, Dr. Reinhard,Rausch, Dr. Alexandra,Schmidt, Dra. Nicole,Siebeneicher, Dr. H
申请号：
CU20170073
公开号：
CU20170073A7
申请日:
2015.11.25
申请国别(地区):
CU
年份:
2017
代理人:
摘要：
<；p>； The present invention relates to Compounds of general formula (I) <；/p>； <；p>； SPACE FOR FORMULA <；/p>； <；p>； where: <；/p>； <；p>； R1 represents C1-C6 alkyl, wherein the C1-C6 alkyl radical may be substituted with 1, 2, 3 halogens, or one or two hydroxy groups, a C3-C6 cycloalkyl which may be substituted with 1,2,3 halogens, a radical R6, R7SO2, R7SO or R8O <；/p>； <；p>； o represents a group selected from: <；/p>； <；p>； SPACE FOR FORMULA <；/p>； <；p>； where * represents a site of union of the group with the radical of the molecule； <；/p>；<；p>； R2 and R3 always have the same meaning and at the same time represent hydrogen or C1-C6 alkyl； <；/p>； <；p>； R4 represents halogen, cyano, C1-C6 alkyl, which can be substituted with 1, 2, 3 halogens, a hydroxy or C3-C6 cycloalkyl group which may be substituted by 1, 2, 3 halogens, or a hydroxy group； <；/p>； <；p>； R5 represents hydrogen, halogen or a C1-C6 alkyl which may be substituted with 1, 2, 3 halogens； <；/p>； <；p>； R6 represents a monocyclic saturated heterocycle that may be mono or methyl substituted with 4 to 6 ring atoms, containing one hetero atom or one O, S series heterogroup, SO and SO2； <；/p>；<；p>； R7 represents C1-C6 alkyl, wherein the C1-C6 alkyl radical can be substituted with 1, 2 or 3 halogens, hydroxy or C3-C6 cycloalkyl； or R7 represents C3-C6 cycloalkyl； <；/p>； <；p>； R8 represents C1-C6 alkyl, where the C1-C6 alkyl radical can be substituted with 1,2 or 3 halogens. <；/p>； <；p>； disclose compounds of the general formula (III), <；/p>； <；p>； SPACE FOR FORMULA <；/p>； <；p>； wherein R1, R4 and R5 are as defined in the claims. Said compounds of formula (III) are useful as intermediates for the preparation of compounds of formula (I). <；/p>；<；p>；La presente invención se refiere a Compuestos de fórmula general (I)<；/p>； <；p>；ESPACIO PARA FÓRMULA<；/p>； <；p>；en donde:&l
