Joseph J. Buggy,Wei Chen,Lee Honigberg,David J. Loury,Zhengying Pan,Erik J. Verner
申请号:
US16361494
公开号:
US20200055859A1
申请日:
2019.03.22
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Described herein are irreversible kinase inhibitor compounds, methods for synthesizing such irreversible inhibitors, and methods for using such irreversible inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate irreversible inhibitor of a protein, including a kinase.