Erik Verner;Joseph J. Buggy;David Loury;Wei Chen;Lee Honigberg
发明人:
Lee Honigberg,Erik Verner,Joseph J. Buggy,David Loury,Wei Chen
申请号:
US12594805
公开号:
US08883435B2
申请日:
2008.03.27
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Described herein are irreversible kinase inhibitor compounds, methods for synthesizing such irreversible inhibitors, and methods for using such irreversible inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate irreversible inhibitor of a protein, including a kinase.