Joseph J. Buggy;Wei Chen;Lee Honigberg;Eric Verner;David J. Loury
发明人:
Lee Honigberg,Eric Verner,Joseph J. Buggy,David J. Loury,Wei Chen
申请号:
US13612143
公开号:
US20130018060A1
申请日:
2012.09.12
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Described herein are irreversible kinase inhibitor compounds, methods for synthesizing such irreversible inhibitors, and methods for using such irreversible inhibitors in the treatment of diseases. Further described herein are methods, assays and systems for determining an appropriate irreversible inhibitor of a protein, including a kinase.