Jeffrey, Scott,Burke, Patrick,Howard, Philip Wilson
申请号:
AU2012322613
公开号:
AU2012322613A1
申请日:
2012.10.12
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
This invention relates to pyrrolobenzodiazepines (PBDs), in particular pyrrolobenzodiazepine dimers having a C2-C3 double bond and an aryl group at the C2 position in each monomer unit, and their inclusion in targeted conjugates. The differing substituent groups may offer advantages in the preparation and use of the compounds, particularly in their biological properties and the synthesis of conjugates, and the biological properties of these conjugates.