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Pyrrolobenzodiazepines and targeted conjugates
专利权人:
Seattle Genetics, Inc.;Spirogen Sarl
发明人:
Jeffrey, Scott,Burke, Patrick,Howard, Philip Wilson
申请号:
AU2012322613
公开号:
AU2012322613A1
申请日:
2012.10.12
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
This invention relates to pyrrolobenzodiazepines (PBDs), in particular pyrrolobenzodiazepine dimers having a C2-C3 double bond and an aryl group at the C2 position in each monomer unit, and their inclusion in targeted conjugates. The differing substituent groups may offer advantages in the preparation and use of the compounds, particularly in their biological properties and the synthesis of conjugates, and the biological properties of these conjugates.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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