JEFFREY, SCOTT,BURKE, PATRICK,HOWARD, PHILIP WILSON
申请号：
CA2850375
公开号：
CA2850375A1
申请日:
2012.10.12
申请国别(地区):
CA
年份:
2013
代理人:
摘要：
This invention relates to pyrrolobenzodiazepines (PBDs), in particular pyrrolobenzodiazepine dimers having a C2-C3 double bond and an aryl group at the C2 position in each monomer unit, and their inclusion in targeted conjugates. The differing substituent groups may offer advantages in the preparation and use of the compounds, particularly in their biological properties and the synthesis of conjugates, and the biological properties of these conjugates.
