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NEUTRALISATION D'ANTICORPS MONOCLONAUX CONTRE LE RECEPTEUR NOGO-66 (NGR) ET LEURS UTILISATIONS
专利权人:
ABBOTT LABORATORIES;ABBOTT GMBH & CO. KG
发明人:
MEZLER, MARIO,MOELLER, ACHIM,MUELLER, REINHOLD,MUELLER, BERNHARD K.,GHAYUR, TARIQ,BARLOW, EVE H.,SCHMIDT, MARTIN,MEYER, AXEL,TEUSCH, NICOLE
申请号:
CA2670368
公开号:
CA2670368C
申请日:
2007.11.21
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The subject invention relates to isolated proteins, particularly monoclonal antibodies, which bind to the Nogo-66 receptor. Specifically, these antibodies have the ability to inhibit the binding of the natural ligand of the Nogo-66 receptor and neutralize the Nogo-66 receptor. These antibodies or portions thereof of the invention are useful for detecting NgR and for inhibiting NgR activity, for example in a human suffering from a disorder in which NgR or Nogo-66 activity is detrimental.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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