Martin Gilbert Pomper;John L. Musachio;Alan P. Kozikowski;Jiazhong Zhang
发明人:
Martin Gilbert Pomper,Jiazhong Zhang,John L. Musachio,Alan P. Kozikowski
申请号:
US13537789
公开号:
US20120276007A1
申请日:
2012.06.29
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to compounds particularly asymmetric urea compounds which are labeled with one or more radioisotopes and which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors which express NAALADase and/or PSMA. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled compounds of the invention, particularly tissues, organs, or tumors which express NAALADase and/or PSMA to which the compounds of the invention have an affinity.