THE JOHNS HOPKINS UNIVERSITY;GEORGETOWN UNIVERSITY
发明人:
POMPER, MARTIN G.,ZHANG, JIAZHONG,KOZIKOWSKI, ALAN P.,MUSACHIO, JOHN L.
申请号：
CA2473289
公开号：
CA2473289C
申请日:
2003.01.10
申请国别(地区):
CA
年份:
2014
代理人:
摘要：
The present invention relates to compounds particularly asymmetric ureacompounds of formula(see formula I)which are labelled with one or more radioisotopes and which are suitable forimaging ortherapeutic treatment of tissues, organs, or tumors which express NAALADaseand/or PSMA. Inanother embodiment, the invention relates to methods of imaging tissues,organs, or tumors usingradiolabelled compounds of the invention, particularly tissues, organs, ortumors, which expressNAALADase and/or PSMA to which the compounds of the invention have anaffinity. Inanother embodiment, the invention relates to pharmaceutical compositionscontaining ureacompounds.
