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IMAGING AGENTS AND METHODS OF IMAGING NAALADASE OR PSMA
专利权人:
The Johns Hopkins University
发明人:
MARTIN GILBERT POMPER,JIAZHONG ZHANG,ALAN P. KOZIKOWSKI,JOHN L. MUSACHIO
申请号:
US14285282
公开号:
US20150079001A1
申请日:
2014.05.22
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to compounds particularly asymmetric urea compounds which are labeled with one or more radioisotopes and which are suitable for imaging or therapeutic treatment of tissues, organs, or tumors which express NAALADase and/or PSMA. In another embodiment, the invention relates to methods of imaging tissues, organs, or tumors using radiolabeled compounds of the invention, particularly tissues, organs, or tumors which express NAALADase and/or PSMA to which the compounds of the invention have an affinity.
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