THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
FRANCIS, YITSHAK,FA, MAURO,ARANCIO, OTTAVIO,FIORITO, JOLE,DENG, SHIXIAN,LANDRY, DONALD, W.,LUZAC, MICHAL,FENG, YAN
申请号:
EP11850544
公开号:
EP2654428A4
申请日:
2011.12.22
申请国别(地区):
EP
年份:
2014
代理人:
摘要:
The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.