THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
发明人:
Ottavio ARANCIO,Shi Xian DENG,Donald W. LANDRY,Jole FIORITO,Rosa PURGATORIO,Owen Anthony O'CONNOR,Jennifer Effie AMENGUAL,Owen Anthony OCONNOR
申请号:
US15868458
公开号:
US20180360842A1
申请日:
2018.01.11
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tau protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.