The Trustees of Columbia University in the City of New York
发明人:
Ottavio ARANCIO,Shixian DENG,Donald W. LANDRY,Jole FIORITO,Rosa PURGATORIO,Owen Anthony O'CONNOR,Jennifer Effie AMENGUAL
申请号:
US16700693
公开号:
US20200101078A1
申请日:
2019.12.02
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The invention provides compounds and compositions comprising compounds that modulate histone acyl transferase (HAT). The invention further provides methods for treating neurodegenerative disorders, conditions associated with accumulated amyloid-beta peptide deposits, Tan protein levels, and/or accumulations of alpha-synuclein as well as cancer by administering a compound that modulates HAT to a subject.