BENNETT, Michael,BETANCORT, Juan,BOLOOR, Amogh,KALDOR, Stephen,STAFFORD, Jeffrey,VEAL, James
申请号:
LT17175464
公开号:
LT3290407T
申请日:
2014.10.17
申请国别(地区):
LT
年份:
2020
代理人:
摘要:
The present invention relates to substituted heterocyclic derivative compounds, compositions comprising said compounds, and the use of said compounds and compositions for epigenetic regulation by inhibition of bromodomain-mediated recognition of acetyl lysine regions of proteins, such as histones. Said compositions and methods are useful for the treatment of cancer and neoplastic disease.