PROBLEM TO BE SOLVED: To provide a novel compound having NPY Y5 receptor antagonism.SOLUTION: The compound is represented by formula (I) (wherein X is -SO2- or the like Y1 is =C(-R8)- or the like Y2 is -C(-R3)= or the like Y3 is =C(-R1)- or the like Z is -N= or the like R1, R3, R8, R9, R11, and R12 are each hydrogen or the like R2 is an optionally substituted alkyl group or the like R4 is an optionally substituted aryl group or the like R5 is an optionally substituted aryl group and n is 1 or the like) and has been found to have NPY Y5 receptor antagonism.COPYRIGHT: (C)2012,JPO&INPIT【課題】新規なNPY Y5受容体拮抗作用を有する化合物を提供する。【解決手段】式(I):(式中、Xは-SO2-等、Y1は=C(-R8)-等、Y2は-C(-R3)=等、Y3は=C(-R1)-等、Zは-N=等、R1、R3、R8、R9、R11及びR12はそれぞれ独立して水素等、R2は置換若しくは非置換のアルキル等、R4は置換若しくは非置換のアリール等、R5は置換若しくは非置換のアリール等、nは1等。)で示される基)で示される化合物が、NPY Y5受容体拮抗作用を有することを見出した。【選択図】なし
