The present invention discloses novel cyclohexane derivatives having NPY Y5 receptor antagonistic activity. Specifically, the present invention discloses a compound represented by the formula (I), or a pharmaceutically acceptable salt or a solvate thereof:wherein A is substituted or unsubstituted aryl or heterocyclyl a combination of X and Y is a combination selected from (X, Y)═(C(═O)N(R1), C(═O)N(R2)), (C(═O)N(R1), imidazole-1,3-diyl), (N(R1), C(═O)N(R2)), (O, C(═O)N(R2)), (C(R3)(R4), N(R2)) or (a single bond, C(═O)N(R2)) R1, R2 and R3 are independently hydrogen or substituted or unsubstituted alkyl R5 is substituted or unsubstituted aryl or heterocyclyl R6 is halogen, oxo, substituted or unsubstituted alkyl, substituted or unsubstituted alkoxy, substituted or unsubstituted aryloxy m is 0 or 1 and n is an integer of 0 to 5 and B is aromatic carbocycle, monocyclic heterocycle or fused bicyclic heterocycle.
