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Pharmaceutical composition for intrannasal delivery comprising anticancer agent-loaded nanoparticles to treat brain disease
专利权人:
IUCF-HYU (INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY);한양대학교 산학협력단
发明人:
LEE, SANG KYUNG,이상경,LEE, KUEN YONG,이근용,YUN, CHAE OK,윤채옥,LEE, MIN HYUNG,이민형,CHUNG, KUN HO,정건호,IRFAN IRFAN ULLAH,이르판울라,LEE, SANG KYUNGKR,LEE, KUEN YONGKR,YUN, CHAE OKKR,LEE, MIN HYUNGKR,CHUNG, KUN HOKR,IRFAN IRFAN ULLAHPK
申请号:
KR1020170056154
公开号:
KR1020170133257A
申请日:
2017.05.02
申请国别(地区):
KR
年份:
2017
代理人:
摘要:
The present invention relates to a pharmaceutical composition for intranasal delivery comprising anticancer agent-loaded nanoparticles to treat brain diseases. More specifically, according to the present invention, nanoparticles containing an anticancer agent are administered to the nasal cavity to transmit the anticancer agent only to the brain cells, thereby enhancing the therapeutic effect of brain tumor and reducing the cytotoxicity of normal cells by an organic solvent used for conventional anticancer agent delivery.본 발명은 항암제 함유 나노입자를 포함하는 뇌질환 치료를 위한 비강 투여용 약제학적 조성물에 관한 것으로, 보다 상세하게는, 항암제를 함유하는 나노입자를 비강 투여하여 뇌세포에만 항암제가 전달되도록 하여 뇌종양 치료적 효과를 높이고, 기존의 항암제 전달에 사용된 유기용매에 의한 정상세포의 세포독성을 줄이는 효과를 제공한다.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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