FRIEDMAN, MARC D.,SHERR, EVAN,KAMAEV, PAVEL,EDDINGTON, WILLIAM,MULLER, DAVID,USHER, DAVID,PERTAUB, RADHA,HEREKAR, SATISH
申请号：
EP13819425
公开号：
EP2872082A4
申请日:
2013.03.15
申请国别(地区):
EP
年份:
2016
代理人:
摘要：
A method for controlling activation of Riboflavin applied to an eye includes applying the Riboflavin to a selected region of a cornea of the eye and initiating cross-linking activity in the selected region by activating the Riboflavin with pulsed light illumination. The pulsed light illumination has an irradiance, dose, and an on/off duty cycle. The irradiance, the dose, and the on/off duty cycle are adjusted in response to a determination of photochemical kinetic pathways for Riboflavin cross-linking activity and to control photochemical efficiency.
