Marc D. Friedman,Evan Sherr,Pavel Kamaev,William Eddington,David Muller,David Usher,Radha Pertaub,Satish Herekar
申请号:
US13841617
公开号:
US20130245536A1
申请日:
2013.03.15
申请国别(地区):
US
年份:
2013
代理人:
摘要:
A method for controlling activation of a cross-linking agent applied to an eye includes applying the cross-linking agent to a selected region of a cornea of the eye and initiating cross-linking activity in the selected region by activating the cross-linking agent with pulsed light illumination. The pulsed light illumination has a selectable wavelength, irradiance, dose, and on/off duty cycle. The wavelength, the irradiance, the dose, and the on/off duty cycle are adjusted in response to a determination of photochemical kinetic pathways for cross-linking activity and to control photochemical efficiency, depth of cross-linking, and density of cross-linking.