Marc D. Friedman,Pavel Kamaev,Evan Sherr,William Eddington,Sara Rood-Ojalvo,David Muller
申请号：
US13665495
公开号：
US09707126B2
申请日:
2012.10.31
申请国别(地区):
US
年份:
2017
代理人:
摘要：
A method for controlling activation of Riboflavin applied to an eye includes applying the Riboflavin to a selected region of a cornea of the eye and initiating cross-linking activity in the selected region by activating the Riboflavin with pulsed light illumination. The pulsed light illumination has an irradiance, dose, and an on/off duty cycle. The irradiance, the dose, and the on/off duty cycle are adjusted in response to a determination of photochemical kinetic pathways for Riboflavin cross-linking activity and to control photochemical efficiency.
