ZHANG, PENGLIE,PENNELL, ANDREW M. K.,WRIGHT, JOHN J. KIM,CHEN, WEI,LELETI, MANMOHAN R.,LI, YANDONG,LI, LIANFA,XU, YUAN
申请号:
HK09101322.8
公开号:
HK1124241B
申请日:
2009.02.12
申请国别(地区):
HK
年份:
2013
代理人:
摘要:
Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are generally aryl piperazine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated diseases, and as controls in assays for the identification of competitive CCR1 antagonists.