3-(imidazolyl)-pyrazolo[3,4-b] pyridines

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专利权人:

Penglie Zhang;Andrew M. K. Pennell;Lianfa Li

发明人:

Lianfa Li,Andrew M. K. Pennell,Penglie Zhang

申请号：

US13103993

公开号：

US08481545B2

申请日:

2011.05.09

申请国别(地区):

US

年份:

2013

代理人:

摘要：

Compounds are provided that act as potent antagonists of the CCR1 receptor, and have in vivo anti-inflammatory activity. The compounds are 3-imidazoyl-pyrazolo[3,4-b]pyridine derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR1-mediated disease, and as controls in assays for the identification of competitive CCR1 antagonists.

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