Recombinant escherichia coli strains

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专利权人:

发明人:

申请号：

EP12001091.3

公开号：

EP2628793A1

申请日:

2012.02.17

申请国别(地区):

EP

年份:

2013

代理人:

摘要：

The present invention is directed to a recombinant E. coli Nissle 1917 (EcN) cell transformed with a nucleic acid coding for a defensin protein or a derivative thereof. The invention is further directed to a pharmaceutical composition comprising this cell and a pharmaceutically acceptable carrier as well as a method of producing a recombinant E. coli Nissle 1917 cell and its use in the treatment of Crohns disease.

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