Tobias Ölschläger,Ean Jeong Seo,Jan Wehkamp,Eduard F. Stange,Ulrich Sonnenborn,Jürgen Malinka,Hans Proppert
申请号：
US14377605
公开号：
US20160015781A1
申请日:
2013.02.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention is directed to a recombinant E. coli Nissle 1917 (EcN) cell transformed with a nucleic acid coding for a defensin protein or a derivative thereof. The invention is further directed to a pharmaceutical composition comprising this cell and a pharmaceutically acceptable carrier as well as a method of producing a recombinant E. coli Nissle 1917 cell and its use in the treatment of Crohns disease.
