Olschlager, Tobias,Seo, Ean Jeong,Wehkamp, Jan,Stange, Eduard F.,Sonnenborn, Ulrich,Malinka, Jurgen,Proppert, Hans
申请号:
AU2013220738
公开号:
AU2013220738A1
申请日:
2013.02.14
申请国别(地区):
AU
年份:
2014
代理人:
摘要:
The present invention is directed to a recombinant E. coli Nissle 1917 (EcN) cell transformed with a nucleic acid coding for a defensin protein or a derivative thereof. The invention is further directed to a pharmaceutical composition comprising this cell and a pharmaceutically acceptable carrier as well as a method of producing a recombinant E. coli Nissle 1917 cell and its use in the treatment of Crohns disease.