DAWSON DAVID W,KURDISTANI SIAVASH K,SELIGSON DAVID B
申请号：
IN4532/KOLNP/2011
公开号：
IN2011KN04532A
申请日:
2011.11.04
申请国别(地区):
IN
年份:
2012
代理人:
摘要：
The present invention provides methods of diagnosing and providing a prognosis and therapy for cancer including, but not limited to, pancreatic cancer and responsiveness to thymidylate synthase inhibitor (e.g., 5- FU) therapy, by identifying cancers with altered histone modification patterns selected from the group consisting of H3K4me2, H3K9me2, or H3K18ac.
