EULJI UNIVERSITY INDUSTRY ACADEMY COOPERATION FOUNDATION
发明人:
CHO, DU HYONG,조두형,CHO, DU HYONGKR
申请号：
KR1020160042624
公开号：
KR1017799330000B1
申请日:
2016.04.07
申请国别(地区):
KR
年份:
2017
代理人:
摘要：
Disclosed is a method for predicting or diagnosing degenerative brain diseases, by detecting phosphorylation on the 293^rd residue on serine in neuronal nitric oxide synthase (nNOS). Moreover, disclosed is a pharmaceutical composition for preventing or treating degenerative diseases containing, as an active ingredient, an inhibitor of cyclin-dependent kinase 5 (CDK5) which phosphorylates the 293^rd residue on serine in nNOS.nNOS(neuronal nitric oxide synthase)의 세린(serine) 293번 잔기의 인산화 여부를 검지하여 퇴행성 뇌질환을 진단 또는 예측하는 방법과, nNOS(neuronal nitric oxide synthase)의 세린(serine) 293번 잔기를 인산화하는 CDK5(cyclin-dependent kinase 5) 저해물질을 유효성분으로 함유하는 퇴행성 뇌질환 예방 또는 치료용 약학 조성물이 개시된다.
