David W. Dawson,Siavash K. Kurdistani,David B. Seligson,DAWSON DAVID W,KURDISTANI SIAVASH K,SELIGSON DAVID B
申请号：
US13262219
公开号：
US20120094949A1
申请日:
2010.04.14
申请国别(地区):
US
年份:
2012
代理人:
摘要：
The present invention provides methods of diagnosing and providing a prognosis and therapy for cancer including, but not limited to, pancreatic cancer and responsiveness to thymidylate synthase inhibitor (e.g., 5-FU) therapy, by identifying cancers with altered histone modification patterns selected from the group consisting of H3K4me2, H3K9me2, or H3K18ac.
