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ELEMENTS REGULATEURS D'ACIDES NUCLEIQUES SPECIFIQUES AU DIAPHRAGME ET METHODES ET UTILISATION ASSOCIEES
专利权人:
VRIJE UNIVERSITEIT BRUSSEL
发明人:
CHUAH, LAY KHIM,VANDENDRIESSCHE, THIERRY,TULALAMBA, WARUT
申请号:
CA3057899
公开号:
CA3057899A1
申请日:
2018.03.27
申请国别(地区):
CA
年份:
2018
代理人:
摘要:
The present invention relates to nucleic acid regulatory elements that are able to enhance diaphragm-specific expression of genes, in particular expression in diaphragm as such, or in combination with expression in cardiac muscle and/or skeletal muscle, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy, more particularly diaphragm-directed gene therapy, and for vaccination purposes.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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