ELEMENTS REGULATEURS D'ACIDE NUCLEIQUE EXPRIME DANS UN MUSCLE, METHODES ET UTILISATION ASSOCIEES

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专利权人:

VRIJE UNIVERSITEIT BRUSSEL;VIB VZW;UNIVERSITEIT GENT

发明人:

VANDENDRIESSCHE, THIERRY,CHUAH, MARINEE,DE BLESER, PIETER

申请号：

CA2936726

公开号：

CA2936726A1

申请日:

2015.01.21

申请国别(地区):

CA

年份:

2015

代理人:

摘要：

The present invention relates to nucleic acid regulatory elements that are able to enhance muscle-specific expression of genes, in particular expression in cardiac muscle and/or skeletal muscle, methods employing these regulatory elements and uses of these elements. Expression cassettes and vectors containing these nucleic acid regulatory elements are also disclosed. The present invention is particularly useful for applications using gene therapy, more particularly muscle-directed gene therapy, and for vaccination purposes.

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