Donald M. Miller,Shelia Diann Thomas,Kara Joyce Sedoris
申请号：
US13063509
公开号：
US08410070B2
申请日:
2009.09.11
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Quadruplex-forming guanine-rich nucleic acid sequences are useful in compositions and methods for inhibiting cellular growth and proliferation and inducing cell death. Compositions for treating a patient are provided, including (i) a safe and effective amount of a sequence having at least 80% nucleic acid identity with a guanine-rich promoter gene oligonucleotide (GPGO), and (ii) a carrier, wherein the oligonucleotide forms at least one quadruplex.
