MAXIM EGOROV,JEAN-YVES GOUJON,RONAN LE BOT,EMMANUELLE DAVID
申请号:
PT15801727
公开号:
PT3237015T
申请日:
2015.11.20
申请国别(地区):
PT
年份:
2019
代理人:
摘要:
The invention relates to hydrosoluble hydroxybisphosphonic derivatives of doxorubicin of formula (I) and the pharmaceutically acceptable salts thereof. The invention also relates to the use of said compounds as a drug, especially in the treatment of a bone tumour. The invention further relates to the pharmaceutical compositions comprising such compounds, the methods for the synthesis thereof and synthesis intermediates.