Composés de cyclooctyne condensés et leur utilisation dans des click-réactions non métalliques

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专利权人:

SYNAFFIX B.V.

发明人:

申请号：

EP11720197.0

公开号：

EP2563753B9

申请日:

2011.04.26

申请国别(地区):

EP

年份:

2016

代理人:

摘要：

The invention relates to fused cyclooctyne compounds, and to a method for their preparation. The invention also relates to a conjugate wherein a fused cyclooctyne compound according to the invention is conjugated to a label, and to the use of these conjugates in bioorthogonal labeling, imaging and/or modification, such as for example surface modification, of a target molecule. The invention further relates to a method for the modification of a target molecule, wherein a conjugate according to the invention is reacted with a compound comprising a 1,3-dipole or a 1,3-(hetero)diene.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/