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Composés de cyclooctyne condensés et leur utilisation dans des click-réactions non métalliques
专利权人:
SYNAFFIX B.V.
发明人:
申请号:
EP11720197.0
公开号:
EP2563753B9
申请日:
2011.04.26
申请国别(地区):
EP
年份:
2016
代理人:
摘要:
The invention relates to fused cyclooctyne compounds, and to a method for their preparation. The invention also relates to a conjugate wherein a fused cyclooctyne compound according to the invention is conjugated to a label, and to the use of these conjugates in bioorthogonal labeling, imaging and/or modification, such as for example surface modification, of a target molecule. The invention further relates to a method for the modification of a target molecule, wherein a conjugate according to the invention is reacted with a compound comprising a 1,3-dipole or a 1,3-(hetero)diene.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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