VAN DELFT FLORIS LOUIS,RUTJES FLORIS PETRUS JOHANNES THEODORUS,DOMMERHOLT FREDERIK JAN
申请号：
IN9272/DELNP/2012
公开号：
IN2012DN09272A
申请日:
2012.10.26
申请国别(地区):
IN
年份:
2016
代理人:
摘要：
The invention relates to fused cyclooctyne compounds and to a method for their preparation. The invention also relates to a conjugate wherein a fused cyclooctyne compound according to the invention is conjugated to a label and to the use of these conjugates in bioorthogonal labeling imaging and/or modification such as for example surface modification of a target molecule. The invention further relates to a method for the modification of a target molecule wherein a conjugate according to the invention is reacted with a compound comprising a 1 3 dipole or a 1 3 (hetero)diene.
