The derivatives of 3,5-dihydroxypentanoate disclosed in the present invention are characterized as compositions having the functions of improving bone formation, and more particularly to the derivatives independent of the mevalonate pathway.本發明揭示一種3,5-二羥基戊酸的類似物,其組成具有改善成骨作用,可不經由甲羥戊酸途徑。