<；P>；PROBLEM TO BE SOLVED: To provide an agent effectively promoting osteogenesis, suppressing bone resorption or increasing bone strength, to provide a preventive and/or improving agent of osteoporosis based on osteogenesis promoting action, bone resorption suppressing action or bone strength increasing action, and to provide a composition of an industrially effectively usable embodiment. <；P>；SOLUTION: An osteogenesis promoting agent, a bone resorption suppressing agent or a bone strength increasing agent, containing thioctic acid and creatine, preferably containing thioctic acid, creatine, and oyster flesh or the like is provided, an osteogenesis preventing and improving agent based on at least one action of osteogenesis promoting action, bone resorption suppressing action and bone strength increasing action is provided, and oral compositions such as foods and drinks compounded with at least one of the agents are provided. <；P>；COPYRIGHT: (C)2009,JPO&INPIT
