Soluble tumor necrosis factor receptor mutant

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专利权人:

Jinsong Wu;Fang Wu;Yijun Shen;Yanjun Liu;Tong Yang

发明人:

Yanjun Liu,Tong Yang,Yijun Shen,Jinsong Wu,Fang Wu

申请号：

US12745724

公开号：

US08454969B2

申请日:

2009.01.12

申请国别(地区):

US

年份:

2013

代理人:

摘要：

A soluble tumor necrosis factor receptor 2 (TNFRII) mutant has an amino acid substitution at position 92Glu compared with the wild TNFRII. The mutant improves the cytotoxicity capacity of neutralizing TNFalpha and lymphotoxin. The mutant and fusion protein comprising it are useful for the treatment of TNFalpha and lymphotoxin related diseases.

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中国工程科技知识中心

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