A soluble tumor necrosis factor receptor mutant

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专利权人:

Taizhou Fudan-Zhangjiang Pharmaceutical Co.;Shanghai Fudan-Zhangjiang Bio-Pharmaceutical Co., Ltd.; Ltd.;Taizhou Fudan-Zhangjiang Pharmaceutical Co., Ltd.

发明人:

Wu, Fang,Yang, Tong,Shen, Yijun,Liu, Yanjun,Wu, Jinsong

申请号：

AU2009253623

公开号：

AU2009253623B2

申请日:

2009.01.12

申请国别(地区):

AU

年份:

2013

代理人:

摘要：

A soluble tumor necrosis factor receptor 2 (TNFRII) mutant has an amino acid substitution at position 92Glu compared with the wild TNFRII. The mutant improves the cytotoxicity capacity of neutralizing TNFalpha and lymphotoxin. The mutant and fusion protein comprising it are useful for the treatment of TNFalpha or lymphotoxin related diseases.

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中国工程科技知识中心

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http://www.ckcest.cn/home/