Georg Fertig,Jens Fischer,Guy Georges,Klaus Kaluza,Valeria Lifke,Joerg Moelleken,Sonja Offner,Achal Pashine,Stefan Seeber
申请号：
US13402399
公开号：
US20120213774A1
申请日:
2012.02.22
申请国别(地区):
US
年份:
2012
代理人:
摘要：
An antibody binding to IL33R characterized in that the heavy chain variable domain comprises a CDR3 region of SEQ ID NO:1, a CDR2 region of SEQ ID NO:2 and a CDR1 region of SEQ ID NO:3 and in that the light chain variable domain comprises a CDR3 region of SEQ ID NO:4, a CDR2 region of SEQ ID NO:5 and a CDR1 region of SEQ ID NO:6 or a chimeric, humanized or T cell epitope depleted antibody variant thereof has advantageous properties for the treatment of inflammatory diseases.
