An antibody specifically binding to human thymic stromal lymphopoietin receptor (TSLPR), characterized in comprising as heavy chain variable domain CDR regions a CDR1 region of SEQ ID NO:2 or 17, a CDR2 region of SEQ ID NO:3 or 10, and CDR3 region of SEQ ID NO:4, and as light chain variable domain CDR regions a CDR1 region of SEQ ID NO:6 or 12, a CDR2 region of SEQ ID NO:7, 13 or 15, and a CDR3 region of SEQ ID NO:8 is useful for the treatment of immunological diseases.本發明係關於一種專一性結合人類胸腺基質淋巴生成素受體(TSLPR)之抗體,其特徵在於包含作為重鏈可變結構域CDR區之SEQ ID NO:2或17之CDR1區、SEQ ID NO:3或10之CDR2區、及SEQ ID NO:4之CDR3區,以及作為輕鏈可變結構域CDR區之SEQ ID NO:6或12之CDR1區、SEQ ID NO:7、13或15之CDR2區、及SEQ ID NO:8之CDR3區,其可用於治療免疫疾病。(無元件符號說明)