FERTIG, GEORG,FISCHER, JENS,GEORGES, GUY,KALUZA, KLAUS,LIFKE, VALERIA,MOELLEKEN, JOERG,OFFNER, SONJA,PASHINE, ACHAL,SEEBER, STEFAN
申请号：
TW101105896
公开号：
TW201238976A
申请日:
2012.02.22
申请国别(地区):
TW
年份:
2012
代理人:
摘要：
An antibody binding to IL33R characterized in that the heavy chain variable domain comprises a CDR3 region of SEQ ID NO: 1, a CDR2 region of SEQ ID NO: 2 and a CDR1 region of SEQ ID NO: 3 and in that the light chain variable domain comprises a CDR3 region of SEQ ID NO: 4, a CDR2 region of SEQ ID NO: 5 and a CDR1 region of SEQ ID NO: 6 or a a chimeric, humanized or T cell epitope depleted antibody variant thereof has advantageous properties for the treatment of inflammatory diseases.
