abstract the present invention relates to a peptide inhibiting a matrix metalloproteeanases activity and use thereof. the peptide inhibiting the matrix metalloproteanases activity exhibits an excellent efficacy of improving the condition of skin by directly inhibiting the matrix metalloproteanases activity. in addition, a composition containing the peptide of the invention has excellent bioactivities of inhibiting the activity of hyaluronic acid degrading enzymes, adipogenesis in fat cells, angiogenesis, and the like, thus being useful for the treatment of various disease such as anti-obesity, anti-cancer, anti-inflammation, and the like, and skin permeability is excellent due to the small size of the peptide, hence being useful in various fields. the peptide of the invention having excellent activity and safety can be advantageously applied to drugs, quasi-drugs, and cosmetics. Peptide that inhibits matrix metalloproteinases activity and use thereof. The present invention relates to a peptide that inhibits the activity of matrix metalloproteinases and their use. The peptide that inhibits the activity of matrix metalloproteinases exhibits excellent efficacy in improving skin condition by directly inhibiting the activity of matrix metalloproteinases. In addition, a composition containing the peptide of the invention has excellent bioactivities of inhibiting the activity of hyaluronic acid degrading enzymes, fat cell adipogenesis, angiogenesis, and the like, thus being useful for the treatment of various diseases such as obesity, cancer, inflammation, and the like, and skin permeability is excellent due to the small size of the peptide, thus being useful in various fields. The peptide of the invention with excellent activity and safety may be advantageously applied to drugs, pseudopharmaceuticals, and cosmetics.abstract the present invention relates to a peptide inhibiting a matrix metalloproteanases activity and use thereof. the peptide inhibiting a matrix metallopro