Provided is a preventing, improving or treating agent for retina disease, comprising geranylgeranylacetone 0.00001 to 95 weight %, wherein the geranylgeranylacetone is a geometrical isomer mixture containing (a) only one specific geranylgeranylacetone geometrical isomer, or (b) one specific geranylgeranylacetone geometrical isomer being equal to or more than 80 weight %, and having a great effect on preventing, improving or treating retina disease.一種視網膜疾病之預防、改善或治療劑,其係含有香葉基香葉基丙酮0.00001至95重量%,該香葉基香葉基丙酮為(a)只有特定之1種香葉基香葉基丙酮幾何異構物,或(b)含有特定之1種香葉基香葉基丙酮幾何異構物80重量%以上之香葉基香葉基丙酮幾何異構物混合物,係於實用上充分地發揮有效預防、改善或治療視網膜疾病之效果者。本案申請專利範圍第1項為一種視網膜疾病之預防、改善或治療劑,本案圖式表示本案實施例之結果的圖表、照片,不足以代表本案技術特徵。