The invention relates to compounds of formula (I): and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and methods of using the compounds of formula (I) as well as pharmaceutical compositions containing such compounds. The compounds may be useful in treating diseases and conditions mediated by TRPA1, such as pain.本發明係關於式(I)化合物: 及其醫藥學上可接受之鹽。另外,本發明係關於製造該式(I)化合物之方法及使用該式(I)化合物之方法以及含有該等化合物之醫藥組合物。該等化合物可適用於治療由TRPA1介導之疾病及病狀,諸如疼痛。