The United States of America, as represented by the Secretary, Department of Health and Human Services;SRI INTERNATIONAL
发明人:
WAINER, Irving W.,BERNIER, Michel,TOLL, Lawrence Robert,JIMENEZ, Lucita Arenas
申请号：
AU2014210656
公开号：
AU2014210656B2
申请日:
2014.08.08
申请国别(地区):
AU
年份:
2016
代理人:
摘要：
#$%^&*AU2014210656B220160317.pdf#####THE USE OF FENOTEROL AND FENOTEROL ANALOGUES IN THE TREATMENT OF GUOBLASTOMAS AND ASTROCYTOMAS ABSTRACT This disclosure concerns the discovery of the use of fenoterol and (R；R)- and {RS)fenoterol analogues for the treatment of a tumor expressing a p2-adrenergic receptor, such as a primary brain tumor, including a glioblastoma or astrocytoma expressing a 02adrenergic receptor, In one example, the method includes administering to a subject a therapeutically effective amount of fenoterol, a specific fenoterol analogue or a combination thereof to reduce one or more symptoms associated with the tumor, thereby treating the tumor in the subject. %45230iG ~ F14s) PS9AV1 MAREE WnaI / I r ci R Nj I I t i '~1 QC ~fl CI' ~N 0 00 N 0 N p. 1/1
