595248 Disclosed herein is a compound of formula I, wherein the variables are defined in the specification, and the use thereof in the treatment of cognitive deficit in schizophrenia, narcolepsy, obesity, attention deficit hyperactivity disorder, pain, Alzheimer&rsquos disease, or a disorder in which modulating the histamine H3 receptor is beneficial. In a preferred embodiment the compound is 4-{ (1S, 2S)-2-[((R)-4-cyclobutyl-2-methylpiperazin-1- yl)carbonyl]cyclopropyl} -benzamide.
