H3 receptor inhibitor histamine, therapeutic use and production

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专利权人:

イーライ リリー アンド カンパニー

发明人:

シンシア・ダーシニ・ジェスダソン,フレディ・クレイグ・スティーブンス

申请号：

JP2007536740

公开号：

JP5057982B2

申请日:

2005.10.11

申请国别(地区):

JP

年份:

2012

代理人:

摘要：

The present invention provides novel compounds with histamine-H3 receptor antagonist or inverse agonist activity. In particular, the invention provides a compound of Formula I, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising the compounds, methods of treatment employing these compounds and compositions, and intermediates and methods for making these compounds. The invention provides methods of using compounds and pharmaceutical compositions to treat obesity, cognitive deficiences, narcolepsy, and other histamine H3 receptor-related diseases.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/