ELIS WINFRIED,ETTENBERG SETH,GARNER ANDREW PAUL,KUNZ CHRISTIAN CARSTEN SILVESTER,SEITZ TOBIAS
申请号:
IN4373CHN2014
公开号:
IN4373CHN2014A
申请日:
2014.06.12
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention relates to antibodies or fragments thereof that target an epitope of a HER3 receptor residing in domain 2 of the HER3 receptor to block both ligand dependent and ligand independent signal transduction and tumor growth; and compositions and methods of use thereof.